Extracellular Vesicles in 2025: Shaping the Medicine of Tomorrow Consuelo Borrás, University of Valencia, Spain Microbiota-Derived OMVs: A Novel Mechanism in Brain Function and Alzheimer’s Disease Roosmarijn E Vandenbroucke, Ghent University, Belgium Commensal gut bacteria-derived microvesicles: Mediators of microbe-host crosstalk and vehicles for mucosal drug delivery Simon Carding, Quadram Institute Bioscience, United Kingdom Microbiota Extracellular Vesicles as a Postbiotic Strategy: Recent Findings and Perspectives Laura Baldomà, Universitat de Barcelona, Spain Bacterial Extracellular Vesicles Halt the Progression of Parkinson’s Disease in the Gut Sandra Morais Cardoso, University of Coimbra, Portugal Impact of Maternal Extracellular on Embryo Metabolism: Recent Advances and Perspectives Felipe Vilella, INCLIVA Health Research Institute, Spain Extracellular Vesicles and Mitochondrial Transfer: A Novel Approach for Treating Parkinson’s Disease Amalia Dolga, University of Groningen, The Netherlands The Microbiome’s Secret Handshake: How bacterial EVs hijack immunity and harm the liver in IBD Claudia Günther, Universitätsklinikum Erlangen, Germany Mitochondrial Stress Drives Nucleophagy and the Release of Extracellular Vesicles Carrying DAMPs Carla Lopes, University of Coimbra, Portugal Inverse Association Between Parkinson’s Disease and Cancer: Could Exosomes Be the Missing Link? Magdalena Gorska-Ponikowska, Medical University of Gdańsk, Poland Extracellular Vesicles and Mitochondrial Dynamics: Implications in Aging and Pathology Maria Cavinato, University of Innsbruck, Austria Extracellular Vesicles for Treating Lysosomal Storage Disorders Ibane Abasolo, Instituto de Química Avanzanda de Cataluña – CSIC, Spain Redox Modulation in Aging Mediated by Stem Cell-derived Extracellular Vesicles Cristina Mas-Bargues, University of Valencia, Spain Dietary-Derived Exosome-like Nanoparticles: Advances and Perspectives Carla Soler, University of Valencia, Spain Histones as Exosome Membrane Proteins: Their Location and Regulation In Response to Cellular and Mitochondrial Jonathan Gilthorpe, Umeå University, Sweden Extracellular Vesicles in Cardio-Metabolic Therapy: Targeting Hypothalamic NLRP3 to Prevent Obesity-Linked Arrhythmias Ramaroson Andriantsitohaina, University of Montpellier, France Engineered Extracellualr Vesicles for Regeneration and Rejuvenation: Advances and Perspectives Lino Ferreira, Faculdade de Medicina da Universidade de Coimbra and associate laboratory CIBB, Portugal Extracellular Vesicles, Oxidative Stress and Mitochondria: Impact on Retinal Diseases Francisco J. Romero, Hospital General de Requena, Spain