Discussions will revolve around the dual role of EVs in mitochondrial function. They are instrumental in optimizing mitochondrial function by transferring proteins and genetic materials, which is vital for targeted drug delivery. However, they also pose risks by spreading damaged mitochondrial components, contributing to disease progression. The latest research in this field aims at biomarker discovery and regenerative approaches in mitochondrial medicine.
This segment will focus on microbiota-derived EVs and their significant role in health and disease. They facilitate communication among microorganisms and influence host cells, serving as potential biomarkers. These interactions between host-derived EVs and the microbiota offer promising therapeutic strategies for immune modulation, microbial balance restoration, and treating microbiota-related diseases.
Speakers Line-Up
Role of Stem Cell-Derived Extracellular Vesicles to Promote Successful Aging
Consuelo Borrás, University of Valencia, Spain
Extracellular Vesicle Release of Mitochondria in Response to Lysosomal Dysfunction
Åsa B. Gustafsson, University of California San Diego, USA
Engineering Exosomes for Precise Mitochondrial Targeting in Brain Cells: Expanding the Frontiers of Cellular Communication and Therapeutics
Lanrong Bi, Michigan Technological University, USA
Targeting central regulation of obesity with EVs: Breakthrough Approach Nature Metabolism
Ramaroson Andriantsitohaina, University of Montpellier, France
Extracellular Vesicle Production from Muscle-Derived Mesenchymal Stem Cells
Didier Serteyn, Université de Liège, Belgium
Bioinspired, Fully Synthetic Extracellular Vesicles to Optimize Wound Healing
Joachim Pius Spatz, University of Heidelberg, Germany
Mitochondrial DAMPs in EVs: Triggering Early Neuroinflammation in Neurodegeneration
Carla Lopes, University of Coimbra, Portugal
Mouse vs. human cell-derived mitochondria containing extracellular vesicles for delivery to the blood-brain barrier
Devika S. Manickam, Duquesne University, USA
The gut microbe-derived extracellular vesicles (GMEVs)- mitochondria axis in mental disorders: Strengths and weaknesses of new studies
Seyed Davar Siadat, Pasteur Institute of Iran, Iran
The Role of Mitovesicles in the Brain with Mitochondrial Dysfunction
Efrat Levy, NYU Grossman School of Medicine, USA
Microbiota-Derived Extracellular Vesicles in Maternal-Fetal Communication: What We Know?
Justus Reunanen, University of Oulu, Finland
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