A Landmark Reference for the EV and Exosome Community : Extracellular Mitochondria in Health and Disease Book by Carla Lopes
Edited by Carla Lopes and Paulo César da Silva Pinheiro, this volume in the Translational and Applied Bioenergetics Series provides a rigorous and comprehensive overview of a rapidly evolving field: the biology and translational potential of extracellular mitochondria.
For decades, mitochondria were considered strictly intracellular organelles. This book consolidates evidence that mitochondria, intact or fragmented can be released, transferred, and function outside the cell, influencing:
- Intercellular communication
- Immune and inflammatory signaling
- Metabolic reprogramming
- Disease progression in cancer, neurodegeneration, and cardiovascular disorders
- Regenerative and mitochondrial-based therapeutic strategies
Particular attention is given to the interface between extracellular mitochondria and extracellular vesicles (EVs)/exosomes, positioning organelle-level communication as a new dimension of systems medicine.
As Carla Lopes prepares to serve as President of Third World Congress on Targeting Extracellular Vesicles 2026 which will be held in next November in Porto, Portugal this publication offers a strong conceptual and scientific framework for the future of EV research advancing from descriptive profiling to functional bioenergetics and translational application.
The book is published by Academic Press (Elsevier) and can be obtained through: The Elsevier / Academic Press official website