Keynote Speaker 2025 – Prof. Simon Carding

With the unifying theme “Extracellular Vesicles as Architects of Systemic Health and Disease”, Professor Simon Carding’s keynote will serve as a foundational moment for the 2025 edition of the Second World Congress on targeting Extracellular Vesicles. More than an introduction, it is designed to establish a scientific and conceptual framework for the two-day event, one that connects basic biological mechanisms with clinical potential.

Professor Carding’s work exemplifies the shift toward systems-level thinking in extracellular vesicle (EV) research. By focusing on bacterial EVs derived from commensal gut microbiota, his keynote highlights how these vesicles operate at the interface between microbes and the human host, serving as mediators of immune regulation, tissue communication, and systemic health.

Importantly, his translational perspective will underscore how insights from microbial vesicle biology are already being leveraged to:
• Advance the development of biomarker platforms for chronic inflammatory diseases
• Inform novel strategies for targeted drug and vaccine delivery
• Deepen our understanding of how gut–brain and gut–immune axes are regulated via vesicular communication.

By bridging fundamental science, immunology, and therapeutic innovation, Professor Carding’s keynote embodies the interdisciplinary spirit of the congress. It will provide attendees with a coherent scientific narrative, catalyzing discussions on how EVs, from bacterial to human origin, can be harnessed to reshape our approaches to diagnostics, personalized therapy, and regenerative medicine.

This strategic keynote sets the stage for a rich dialogue on how extracellular vesicles are not merely biomarkers or messengers, but central orchestrators of health and disease in the emerging era of precision medicine.