Mitochondrial DAMPs in EVs: Triggering Early Neuroinflammation in Neurodegeneration
Carla Lopes
University of Coimbra, Portugal
Dr. Carla Lopes from the University of Coimbra, Portugal will join the First World Congress on Targeting Extracellular Vesicles.
Topic: Mitochondrial DAMPs in EVs: Triggering Early Neuroinflammation in Neurodegeneration
In her talk, Dr. Lopes will cover the complex interplay between neuroinflammation and neurodegenerative diseases, exploring the roles of aging, genetics, inflammation, oxidative stress, and mitochondrial dysfunction.
She will highlight the pivotal role of microglia as immune sentinels, the emerging significance of extracellular vesicles (EVs) in intercellular signaling, and the impact of mitochondrial-derived vesicles (MDVs) enriched in mitochondrial damage-associated molecular patterns (mtDAMPs) on exacerbating inflammation.
Understanding these mechanisms is crucial for developing effective strategies to address neurodegenerative disorders.
Don't miss out on Dr. Lopes's talk this October in Malta.