Bacterial Extracellular Vesicles Halt the Progression of Parkinson’s Disease in the Gut
Sandra Morais Cardoso
University of Coimbra, Portugal
Dr. Sandra Morais Cardoso from the University of Coimbra, Portugal will present her latest stuty on Bacterial Extracellular Vesicles Halt the Progression of Parkinson’s Disease in the Gut during the Targeting EVs 2025 congress.
About the Talk:
Dr. Cardoso's research demonstrates how BEVs from commensal gut bacteria can effectively modulate disease progression by targeting intestinal inflammation, a potential initiating factor in PD pathology. Results show that BEV supplementation prevents inflammatory immune cell accumulation, preserves gut barrier integrity, reduces α-synuclein aggregation, and protects dopaminergic neurons in the substantia nigra, ultimately preserving motor function.
This gut-targeted approach represents a novel preventative strategy that could address PD at its earliest stages, before neurodegeneration becomes irreversible.